Masu bincike sun gano cewa babban metabolite na Thc ya kasance mai ƙarfi dangane da bayanai daga samfuran linzamin kwamfuta. Sabbin bayanan bincike suna ba da shawarar cewa babban metabolite da jini har yanzu suna aiki kuma mai tasiri kamar yadda Thc, idan ba haka ba ne. Wannan sabon binciken yana haifar da tambayoyi sama da amsoshi. A cewar wani binciken da aka buga kwanan nan da aka buga a cikin jaridar Pharmacology da maganin gwaji, da psycomacy-psychoxite-thc (11-oh-thc), yana da daidai ko mafi girman ilimin halin psychoa fiye da THC (Delta-9 THC).
Nazarin, mai maye "The maye gurbin daidaitaccen na 11-hydroxy-9-OH (11-Oh-thc metabolites yana riƙe aiki. Sanannen abu ne cewa THC ta rushe kuma yana samar da sabon mahaɗan da ban sha'awa lokacin da ta lalata akwatin fuska da aikata shi a jikin mutum. "A cikin wannan binciken, mun yanke shawarar cewa babban metabolite na Thc, 11-Oh-Thc, nunin bambance-bambancen aiki sama da THC a cikin tsarin aikin linzamin kwamfuta lokacin da aka gudanar da shi, da magunguna na magunguna," nazarin jihar. "Waɗannan bayanan suna ba da kyakkyawar fahimta a cikin ayyukan halittar Thc, Ka sanar da bincike na Cannabinoid, da kuma samfurin yadda Tc yake amfani da kayan cannabis na mutane."
An gudanar da wannan binciken daga Saskatchewan, Kanada, gami da Ayat Zagzoog, alayzie Dandyneva, da Robert B. Laprairie. A cikin gwaji, masu bincike sun allura berayen maza tare da 11-hydroxy-tnc da kuma lura da kuma yin nazarin kwayar cutar wannan THC, Delta-9 THC.
Masu binciken sun kara da cewa: "Wadannan bayanan suna nuna cewa a cikin gwajin dala-flick, da kuma a cikin gwajin magunguna, 11-Oh-Thc na nuna kwatankwacin aiki fiye da yadda iyayenta na THC."
Don haka, binciken ya nuna cewa thc metabolite 11-Oh-thc na iya taka muhimmiyar rawa a cikin ayyukan cannabis. Fahimtar aikinta lokacin da aka gudanar kai tsaye zai taimaka wajen bayyana dabba da na nan gaba da na mutum. Rahoton ya ambaci cewa 11-Oh-Thc yana daya daga cikin metabolites biyu na farko wanda aka kafa bayan cinikin Cannabis, ɗayan kuma ba shi da hankali ba amma yana iya kasancewa cikin jini ko fitsari na dogon lokaci.
A cewar cibiyoyin Amurka don sarrafa cuta da rigakafin (CDC), tun da wuri kamar shekarun 1980, Motely-carboxylic acid (9-carberox-9-carboxylic acid 11-norbolite-9-thc, wanda shine babban sinadari mai aiki a Cannabis.
Rahoton ya nuna cewa ko da yake cannabis na cannabis yawanci yana samar da tasirin sauri fiye da cin cannabis na cannabis ya fi girma daga furanni cannabis na cannabis. Rahoton ya nuna cewa wannan shine dalili daya da ya sa abinci mai ban mamaki zai iya zama mafi ƙwaƙwalwa cikin ƙwaƙwalwar ƙwaƙwalwa kuma yana haifar da rikicewa don rashin shiri.
Thc metabolites da gwajin magani
Shaida ta nuna cewa cannabis yana shafar masu amfani daban dangane da hanyar gudanar da gudanarwa. An buga binciken 2021 a cikin jaridar dindindin da aka nuna cewa sakamakon cin cannabis Edabis saboda metabolism na 11-oh-thc.
"Asiavailability na Thc ta hanyar Vaporization shine 10% zuwa 35%," Masu binciken suka rubuta. "Bayan sha, ThC ta shiga hanta, inda aka cire yawancin shi ko kuma sauran abubuwan da ke cikin tarko. Yawanci, da sauri, plasma da sauri. A zahiri, plasma Rabin rayuwa na Thc a cikin masu amfani da lokaci-lokaci shine 1 zuwa 3 kwanaki, yayin da a cikin masu amfani na kullum, zai iya zama tsawon kwanaki 5 zuwa 13. "
Bincike ya nuna cewa dogon bayan psyabis na psyabis na cannabis sun watsar, thc-thc zai iya kasancewa cikin jini da fitsari don tsawan lokaci. Wannan na tasirin kalubale don daidaitattun hanyoyin gwaji ko direbobi da 'yan wasa ne sakamakon amfani da cannabis. Misali, masu binciken Ostireliya sun yi kokarin tantance lokacin da ke cikin tsari a lokacin da cannabis zai iya kawar da wasan tuki. A cikin akwati guda, Thomas R. Akelell, Da Danielle McCartney, da kuma IIIN S. McGGor daga Action Extest a Jami'ar Sydney ta yi nazari kan tasirin cannabis a kan tuki tuki. Tungiyar ta yanke hukunci cewa cannabis ta dace da karfin tuki na awanni da yawa bayan shan taba, amma ana share su a jikin wani makonni ko watanni.
"Marasa lafiya Amfani da samfuran Thc-dauke da tuki da sauran ayyukan da ke da himma (misali, injunan aiki), musamman masu zanga-zangar sun rubuta. "Ko da marasa lafiya ba sa jin rauni, har yanzu suna iya gwada tabbatacce ga THC. Bayan haka, marasa lafiyar cututtukan cututtukan lafiya a halin yanzu ba a keɓance daga gwajin miyagun ƙwayoyi da kuma takunkumi mai dangantaka da takunkumi."
Wannan sabon bincike a kan 11-Oh-thc yana nuna cewa ana buƙatar ƙarin bincike da ake buƙata don fahimtar yadda metabolites ke shafar jikin mutum. Kawai ta ci gaba da ƙoƙarin da za mu iya buɗe asirin waɗannan mahaɗan na musamman.
Lokaci: Mar-21-2025